Covid-19 Vaccine Research, Development, Ingredients and Reactions

[Mykyl]

A couple of stories I have read in the past couple of days. 

I assume this story means that boosters will indeed be needed. https://www.bbc.co.uk/news/health-58322882

 

Quote

Researchers say they are seeing some waning of protection against Covid infections in double-jabbed people. 

———————————————————

Also this…

Covid jab response low for some immunosuppressed people  

 

https://www.bbc.co.uk/news/health-58317261

 

Quote

Some patients with impaired immune systems have a low or absent antibody response after receiving two doses of Covid vaccine, a UK studyhas found. 

Experts do not yet know what that means for protection, but say booster shots are probably a good idea for certain immunosuppressed people.

 

[carlos]

On 8/25/2021 at 12:47 AM, Shawnster said:

Then why is it important to get the annual influenza vaccine?  How is that different than a booster and why is that OK but an annual (or 8 month) covid booster unadvised?

The flu vaccine is not a booster. The flu virus is different every year, so a different vaccine is needed.

[runner92]

On 8/17/2021 at 10:40 AM, Sofia said:

How to measure REAL imunity to Sars Cov 2?

Measuring T-Cells.

Here´s the process:

1. A blood sample is collected using routine phlebotomy and a standard blood collection tube from which a subset of white blood cells, known as peripheral blood mononuclear cells, are isolated. The cells are washed, counted and normalized to create a standard cell suspension.

2. A standard number of cells are added into specially designed plates and stimulated with antigens specific to the disease under study. Cells responding to these antigens release a chemical messenger known as a cytokine.

3. Cytokine antibodies are used to directly capture the cytokine as it is released by the cells. A secondary labeled antibody is added and binds to the captured cytokine.

4. A detection reagent is added and reacts with the secondary labeled antibody. This reaction produces spots, which are a footprint of where the cytokine was released. Spots are then enumerated.

 

The typical methods of detecting T cell immunity to SARS-CoV-2 require expensive, multi-step sample preparation and in vitro T cell stimulation using methods that have not yet been standardized and require highly specialized laboratories. These techniques involve drawing relatively large amounts of blood, isolating T cells from the collected blood, stimulating the isolated T cells with SARS-CoV-2 peptides in tissue culture, and finally analyzing the cultured T cells using sophisticated assays. In the most common technique, called intracytoplasmic cytokine staining (ICS) the analysis instrument is called a multi-parameter flow cytometer.

 

 

No wonder Governments prefer something that measures ANTIBODIES instead. This method is reliable but too expensive and too time consuming. Not practical to use in every person!

 

I hope you all understand why governments insist on vaccine boosts. To boost antibodies. Instead of measuring T cells!!

 

Too much vaccinations against SARS can be harmful causing auto imune disease.

We definatly need the Kingdom! Please let it come!!

 

 

 

here´s more on this:

 

https://www.technologynetworks.com/diagnostics/blog/a-skin-test-to-measure-t-cell-immunity-to-sars-cov-2-347298

 

 

This is why I have been leery of this shot. So many virologists and doctors have expressed from the very beginning significant concerns about many people developing autoimmune disorders during over the next few years after getting this so-called vaccine. Of course, these people were called "conspiracy theorists" and had their pages removed for "misinformation". I can already see they're about to start telling people they'll have to get quarterly shots and if they don't they won't be considered fully vaccinated. 

Edited August 26, 2021 by runner92

[Sofia]

The natural immune protection that develops after a SARS-CoV-2 infection offers considerably more of a shield against the Delta variant of the pandemic coronavirus than two doses of the Pfizer-BioNTech vaccine, according to a large Israeli study that some scientists wish came with a “Don’t try this at home” label. The newly released data show people who once had a SARS-CoV-2 infection were much less likely than vaccinated people to get Delta, develop symptoms from it, or become hospitalized with serious COVID-19.

[Sofia]

The highly touted gene therapy and inactivated virus based intramuscular immunizations are mediocre attempts at what could’ve been done properly.

 

intra nasal imunization:

 

• An intranasal subunit vaccine against SARS-CoV-2 elicits rapid immunity
• •
  Stable single-dose vaccine elicits systematic and mucosal immune responses
• •
  Spike specific IgA responses are present in the nasal compartment and the lung

 

https://www.cell.com/iscience/fulltext/S2589-0042(21)01005-1
 

 

Edited August 27, 2021 by Sofia

[Shawnster]

43 minutes ago, Sofia said:

The natural immune protection that develops after a SARS-CoV-2 infection offers considerably more of a shield against the Delta variant of the pandemic coronavirus than two doses of the Pfizer-BioNTech vaccine, according to a large Israeli study that some scientists wish came with a “Don’t try this at home” label. The newly released data show people who once had a SARS-CoV-2 infection were much less likely than vaccinated people to get Delta, develop symptoms from it, or become hospitalized with serious COVID-19.

Are these your words or is there a source? 

[Sofia]

18 minutes ago, Shawnster said:

Are these your words or is there a source? 

Not my words brother Shawn

Source: https://www.sciencemag.org/news/2021/08/having-sars-cov-2-once-confers-much-greater-immunity-vaccine-no-infection-parties

[Shawnster]

Thanks

[BLEmom]

https://apple.news/AHA8eML4SRSund6u-5OYWqw
This is Apple news but from Bloomberg. Hopefully will open for you. It’s about antibodies and the bodies natural backup t cells. 

[daydream]

https://www.nih.gov/news-events/nih-research-matters/antibodies-t-cells-protect-against-sars-cov-2

Was not able to open up that Bloomberg site but I wonder if this is the same article.

Quote

 

Finally, the researchers tested whether immune cells called T cells play a role in long-term immunity to the virus. They used a drug to deplete T cells in five monkeys that had recovered from SARS-CoV-2, then re-exposed them to the virus. All had evidence of reinfection in the nose, and one had virus in its lungs. In contrast, monkeys with active T cells successfully fought off reinfection.

Antibodies initially produced by the body after infection had started to drop during this period. This finding suggests that T cells are needed for long-term protection from the virus.

“Antibodies alone can protect, including at relatively low levels, but T cells are also helpful if antibody levels are insufficient,”

 

 

[Sofia]

1 minute ago, happiness IS said:

https://www.nih.gov/news-events/nih-research-matters/antibodies-t-cells-protect-against-sars-cov-2

Was not able to open up that Bloomberg site but I wonder if this is the same article.

 

T cells are primary immunity 

they have memory so the are activated when the same virus attacks 

 

on the other hand we don’t need to have PERMANENTLY sars cov 2 antibodies in our bloodstream 🤦‍♀️
 

those T cells activate B cells in our bone marrow to produce more antibodies if necessary 

[BLEmom]

1 hour ago, happiness IS said:

https://www.nih.gov/news-events/nih-research-matters/antibodies-t-cells-protect-against-sars-cov-2

Was not able to open up that Bloomberg site but I wonder if this is the same article.

 

The article I read said info was released August 23rd and was based on Perelman School of medicine research.  Here’s another article quoting the same guy

https://www.reuters.com/business/healthcare-pharmaceuticals/mrna-vaccines-trigger-backup-immune-response-some-cancer-drugs-may-help-2021-08-25/

[Sofia]

Research on COVID-19 published this week:

Delta doubles the risk?

Patients with COVID-19 who are infected with the Delta variant have approximately two times the risk of hospital admission compared with patients with the alpha variant, according to a study from England and twice the risk of developing pneumonia, according to another study from Singapore.

Another variant to keep an eye on

The Mu (B.1.621) variant, first detected in Colombia in January of this year, has been officially listed as variant of interest because of a combination of mutations that could help it evade immunity. However, the WHO and other experts stress that there is no evidence yet that this is the case, and for the moment it accounts for less than 0.1% of all global COVID-19 infections.

The impact of masks

A large randomized trial in Bangladesh, involving more than 340,000 people in 600 villages, shows that interventions promoting the use of face masks reduce the spread of COVID-19, and that surgical masks work better than cloth ones. The interventions tripled the proportion of people who wore masks correctly. In villages where masks were distributed, symptomatic infections were 9.3% lower (11% if surgical masks were given), with older people benefiting the most (35% reduction in symptomatic COVID among people over 60).

Long Covid after 1 year

A prospective study in China with 1276 COVID survivors shows that most (88%) had returned to their original work and had good physical and functional recovery 1 year later, even if half still had at least one symptom. Overall, the health status in the cohort of COVID-19 survivors at 12 months was still lower than that in the control population.

More evidence on cross-protection

Pre-existing T cells generated against human endemic coronaviruses can cross-react with the SARS-CoV-2 Spike protein and enhance immune responses upon SARS-CoV-2 infection and vaccination. These cells’ cross-reactivity decreases with age, which may help explain the incidence of severe infection in elderly.

And on vaccine-mediated protection

A UK study found that, in fully vaccinated people that get infected, the risk of Long COVID was reduced by almost half. There were also fewer hospitalisations (73% less likely) and lower burden of acute symptoms (31% less likely) among those fully vaccinated. Individuals with frail health conditions were up to two times more likely to contract COVID-19 infection after vaccination. People living in most deprived areas were also at greater risk of infection, especially after a single vaccine dose.

In the US, new data from Los Angeles County (May to July 2021) show that unvaccinated people were 5 times more likely to get COVID-19 than vaccinated people, and 29 times more likely to be hospitalized. And, according to hospitalisation rates in the US, unvaccinated adults are 17 times more likely to be hospitalised compared with vaccinated adults, across all age groups and including the period when Delta became dominant.

Finally, another study underscores the importance of community vaccination in protecting unvaccinated children from COVID-19: hospital admissions among US children and adolescents under 17 years of age were highest in those states with lowest vaccination coverage.

15 million deaths

This could be the true death toll of the pandemic – more than 3 times the official 4.6M deaths to date, according to an analysis by The Economist.

5 billion doses

Over 5 billion COVID-19 vaccine doses have been administered globally. But only 1.6% of these have reached low-income countries. This inequity is getting worse as rich nations are offering booster doses to their citizens, while 60% of the world population has not yet received a single dose.

[Brother_Bliss]

4 hours ago, Sofia said:

and that surgical masks work better than cloth ones

Over here, of you go to a doctor or hospital with a cloth mask, they will hand you a surgical mask and ask you to put it on instead. 

 

All masks work, but some masks work better.

[Amygdala]

I don’t know if it’s already been posted, but this morning my Bible study told me she had her first shot of “Comirnaty“. I looked at her vaccine passport on video chat and thought it was a vaccine for another disease she was having to be immunized for. But she insisted it was the first shot against COVID.

 

So after searching online, I saw that Comirnaty is the new vaccine name they are replacing for Pfizer Biontech. 
 

https://www.forbes.com/sites/brucelee/2021/08/23/why-comirnaty-is-the-new-name-for-pfizer-covid-19-vaccines-spikevax-for-moderna/

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The name uses the prefix “co-” to represent community, the “mirna” for mRNA, and the “-ty” as a nod towards the end of both “community” and “immunity.” So the name is supposed to make you think about the technology behind the vaccine, immunity, and community at the same time, rather than one manatee saying to another, “come on, manatee, let’s go party.” Thus, the correct phonetic pronunciation of this new brand name will be koe-mir’-na-tee.

 

[hatcheckgirl]

Yes, our Pfizer shots have shown the Comirnaty name, so I knew that was what I was getting. But I hadn’t known about the meaning. Interesting.

[Shawnster]

49 minutes ago, Dismal_Bliss said:

Over here, of you go to a doctor or hospital with a cloth mask, they will hand you a surgical mask and ask you to put it on instead. 

 

All masks work, but some masks work better.

I've been to the doctor with my cloth mask and nobody said anything. Double layered with a filter in the middle.  My mask looks a lot more durable than those cheap disposable paper masks by the door. 

[Sofia]

57 minutes ago, Dismal_Bliss said:

Over here, of you go to a doctor or hospital with a cloth mask, they will hand you a surgical mask and ask you to put it on instead. 

 

All masks work, but some masks work better.

Here some doctors recommend double masks  (using 2)

[Sofia]

Another innovative mucosal vaccine effort. A thermostable oral SARS-CoV-2 vaccine induces mucosal and protective immunity

 

https://www.biorxiv.org/content/10.1101/2021.09.09.459634v1

[hatcheckgirl]

The Birthing Unit Director of Liverpool Hospital Sydney, and a new mum herself pleaded:
 

I understand the concept of COVID vaccination can be concerning to some and it seems we have approved and implemented the vaccine very quickly, but the technology behind the development of the vaccine has been around for about 10 years. 
 

Many women are worried that the side effects of the vaccine in pregnancy have not been researched enough. 

I want to reassure everyone that the safety profile of the vaccines in pregnancy has been studied extensively.
 

Over 100,000 women were included in studies from the US and the UK.

These have not demonstrated any adverse outcomes for your baby. 

 

The vaccine does not increase the risk of miscarriage or structural abnormalities for your baby.

It does not affect your fertility. 

 

What poses the greatest risk to women and their babies is not the vaccine — it is the COVID-19 infection itself. 

Having COVID-19 while you're pregnant means you're at double the risk of needing an ICU admission, you have an increased risk of needing invasive ventilation and you're at increased risk of requiring a pre-term delivery. 

It also doubles your risk of stillbirth. 

Most of the women who have been admitted at our hospital are unvaccinated and none of them have been fully vaccinated. 
 

Read full article here: 

https://www.abc.net.au/news/2021-09-15/sydney-doctor-makes-plea-for-mums-to-get-vaccinated/100463636

[hatcheckgirl]

Theses figures are telling:

 

In Australia, since vaccinations started in February 2021, there have been 574 ICU admissions. 

 

Only 13 people, or two per cent, had received two doses, while 69 - the equivalent to 12 per cent - had a single shot.

The remaining 492 patients were unvaccinated.

 

Vast majority of ICU patients are unvaccinated https://www.sbs.com.au/news/vast-majority-of-icu-patients-unvaccinated?cid=newsapp:socialshare:copylink
 

 

 

[hatcheckgirl]

2 hours ago, hatcheckgirl said:

Vast majority of ICU patients are unvaccinated https://www.sbs.com.au/news/vast-majority-of-icu-patients-unvaccinated?cid=newsapp:socialshare:copylink

Link is dead.  Here's another one:

https://thewest.com.au/news/coronavirus/hospital-numbers-key-to-easing-lockdowns-c-3965638

[Sofia]

Portugal is the country in the World with highest % population vaccinated 

[trottigy]

4 hours ago, Sofia said:

Portugal is the country in the World with highest % population vaccinated 

Odd, I didn't notice Israel on the list at all. Did I miss it?

[daydream]

https://ycharts.com/indicators/israel_coronavirus_full_vaccination_rate

Israel Coronavirus Full Vaccination Rate

63.29% for Sep 14 2021

 

https://www.houstonpublicmedia.org/npr/2021/08/23/1029628471/highly-vaccinated-israel-is-seeing-a-dramatic-surge-in-new-covid-cases-heres-why/

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4. Israel's high vaccination rate isn't high enough.

The country jumped out ahead of all other countries on vaccines, and 78% of eligible Israelis over 12 years old are vaccinated.

But Israel has a young population, with many under the eligible age for vaccination, and about 1.1 million eligible Israelis, largely between the ages of 12 and 20, have declined to take even one dose of the vaccine.

That means only 58% of Israel's total citizenry is fully vaccinated

 

Quote

More than a million Israelis have received a Pfizer booster shot in the last several weeks. They are being watched around the world, as Israel is the first nation to give a third dose of Pfizer on a mass scale, just as it was ahead of the curve on the first round of shots.