Covid-19 Vaccine Research, Development, Ingredients and Reactions

[Allabord4Jah]

52 minutes ago, Qapla said:

 

With the J&J vaccine there is no "second shot" - it is a single dose vaccine.

 

Your right, my error.  One shot only.  She got one shot.

[dove]

On 4/13/2021 at 9:31 AM, New World Explorer said:

https://www.bbc.com/news/world-us-canada-56733715

Covid-19: US agencies call for pause in Johnson & Johnson vaccine

A sister in her early 40’s in my sil’s congregation got the J&J shot a week ago and 2 hours later began to have bad side effects. This morning she was rushed to the hospital with blood clots. It’s very serious. 

Edited April 16, 2021 by Dove

[Loopy]

We have a young elder that had his 2nd Maderna poke on Friday, a week ago. He developed an allergic reaction, with temperature and swelling of the face to the point his eyes were just slits. I think they said he was to the doctor here in town (twice). 
 

His wife said if he’s not better they’ll go to another doctor in Marquette on Monday. Personally, with our doctors here in town I wouldn’t wait that long. That’s waiting way too long for something  like this. He hasn’t been able, of course, to go to work.

 

 

[WilliamChew]

https://edition.cnn.com/2021/04/16/health/blood-clots-vaccine-possible-cause/index.html

 

Even though the link is not firm yet, they're calling the condition vaccine-induced immune thrombotic thrombocytopenia or VITT. It's characterized by unusual blood clotting combined with a low number of blood-clotting cells called platelets. Patients suffer from dangerous clots and, sometimes, hemorrhaging at the same time.

 

Adenoviruses

Both AstraZeneca's vaccine and the J&J vaccine use common cold viruses called adenoviruses as a carrier and some experts suspect the body's response to those viral vectors might underlie the reaction.

 

Heparin blood thinner

A team led by Dr. Marie Scully, a hematologist at University College London Hospitals, studied 22 patients who developed the syndrome after receiving AstraZeneca's vaccine, and found they had an unusual antibody response. These so-called anti-PF4 antibodies had only been seen before as a rare reaction to the use of the common blood thinner heparin.

 

Treatment

Patients should be given anti-clotting drugs, but not heparin, and infusions of a blood product called intravenous immunoglobulin may replace the depleted platelets.

[hatcheckgirl]

3 hours ago, WilliamChew said:

It's characterized by unusual blood clotting combined with a low number of blood-clotting cells called platelets. Patients suffer from dangerous clots and, sometimes, hemorrhaging at the same time.

This was what I was wondering about - how it manifests with two seemingly opposite symptoms. Clearly, whatever this is has wreaked havoc on our immune system.

 

Remember, it’s not actually the vaccine, but the person’s individual reaction to the virus (which the vaccine is mimicking). So, if you have coronavirus AND you happen to have this type of susceptible immune system, then you will develop blood clots and issues with low platelets.  How absolutely bizarre and frightening this disease is!

[New World Explorer]

48 year woman, died here in Australia, cause of death is likely Astra-Zeneca vaccine (reaction to it) 

 

 

[Sofia]

On 4/17/2021 at 4:30 AM, hatcheckgirl said:

This was what I was wondering about - how it manifests with two seemingly opposite symptoms. Clearly, whatever this is has wreaked havoc on our immune system.

 

Remember, it’s not actually the vaccine, but the person’s individual reaction to the virus (which the vaccine is mimicking). So, if you have coronavirus AND you happen to have this type of susceptible immune system, then you will develop blood clots and issues with low platelets.  How absolutely bizarre and frightening this disease is!

Absolutely correct statements sis 🤗

[Sofia]

On 4/17/2021 at 1:15 AM, WilliamChew said:

Even though the link is not firm yet, they're calling the condition vaccine-induced immune thrombotic thrombocytopenia or VITT. It's characterized by unusual blood clotting combined with a low number of blood-clotting cells called platelets. Patients suffer from dangerous clots and, sometimes, hemorrhaging at the same time.

Antibodies bind to platelets creating trombocitopenia leading to more prone to hemorrhage 

 

On the other hand the platelets binded together create clots themselves.

 

seems acquard but this virus creates havoc at people imune system and reactions are unpredictable 

Edited April 18, 2021 by Sofia

[halfspanishlee]

I got a text 2day from the NHS here in the uk saying to book my Covid Vaccine but to be honest am still in two minds about having my parents my sister have had and now my older brother is gonna gonna take. 

[New World Explorer]

5 hours ago, halfspanishlee said:

I got a text 2day from the NHS here in the uk saying to book my Covid Vaccine but to be honest am still in two minds about having my parents my sister have had and now my older brother is gonna gonna take. 

You have to make a personal decision, do not look for encouraging or discouraging comments here .... It is still your choice to make. 

[vern]

i you had it already in your life...........

[Sofia]

This last week´s news on research:

 

Innocent until proven guilty

Another variant first identified in India (B.1.617) has raised some alarm because it presents two mutations in Spike (E484Q and L452R) that have shown evidence of antibody escape in the laboratory. But there is no evidence yet that the variant is more transmissible or can escape immunity. This variant deserves close monitoring but is not cause for concern, experts say.

Super antibodies

Antibodies obtained from a convalescent COVID-19 patient were found to neutralise multiple SARS-CoV2 variants of concern and SARS. A team from Scripps Institute identifies the binding sites that facilitate cross-reactivity of these antibodies. These findings provide valuable information for designing vaccines and therapeutic antibodies against current and future SARS-related viruses

Lower risk of reinfection

A study with young, healthy US Marine recruits shows that seropositive individuals (i.e. with antibodies to SARS-CoV-2) had about one fifth the risk of subsequent infection as compared with seronegative individuals (10% vs 48%). Furthermore, infected seropositive participants had viral loads that were about 10-times lower than those of infected seronegative participants, meaning they are less likely to transmit.

More on vaccines

Data from Chile

Chile has announced that Sinovac’s vaccine is 80% effective against death and 67% effective against COVID-19 symptoms. Protection after one single dose was much lower. Almost 34% of the country’s population has been fully vaccinated, 93% of which have received the CoronaVac vaccine.

Responses in older people

Single doses of either the Pfizer of the Oxford / AstraZeneca vaccine in older people induce humoral immunity (antibodies) in most donors and are greatly enhanced in those who had a previous infection, according to a study (not yet peer-reviewed) in the UK. Cellular responses (T cells) are weaker but overall better with the AstraZeneca jab.

Yes, vaccines work!

The US CDC has identified some 5,800 cases of SARS-Cov-2 infection among more than 66 million fully vaccinated Americans. These “breakthrough” cases, which are defined as positive PCR results at least two weeks after patients the second dose, represent 0.008% of the fully vaccinated population. 7% of these infections (i.e. 0.00056%) needed hospitalization and only 7 fully vaccinated people died (0.00001%).

Meanwhile, a study on the effects of vaccination among nursing home residents, staff and healthcare workers in Catalonia shows an 85%-96% reduction in SARS-CoV-2 infection in all three cohorts, and even bigger reductions (>95%) in hospitalisations and mortality amongst nursing home residents for up to two months.

A pan-coronavirus vaccine?

Developing a vaccine capable of protecting against known and unknown coronaviruses (at least those pertaining to the beta coronavirus family) is possible, and has suddenly become a top priority. Many teams are currently using different strategies to achieve this goal.

Rare thrombosis cases

EMA’s safety committee concluded that the unusual thrombosis cases linked to the Johnson & Johnson vaccine were very similar to those observed with the AstraZeneca vaccine and that unusual blood clots with low blood platelets should be listed as very rare side effect of the vaccine. The agency emphasised that the overall benefits of the vaccine in preventing COVID-19 outweigh the risks of side effects.

[Br. Ice]

China is considering mixing Covid-19 vaccines. 

 

 

[Hope]

I had my first C-19 jab this afternoon- Pfizer. They were giving them free at my workplace. 

 

I feel pretty good. I might be feeling a little like I just took a swig of rum... 🤔 It's a couple hours later and I just feel sorta tired. 

 

I also discovered that my job is probably ending next Friday, so that could be it, too... 😥  But, I have meeting tonight- gitta get bright!  👍🏼😔

[friendlyone]

I had my second covid-19 vaccination just over one week ago. It's the AstraZeneca vaccine.

 

I have to say I haven't had any adverse reaction at all. I never felt soreness in the arm later at any point. No flu-like symptoms, feeling weak, headaches, nothing at all. It was as though I never had it.

 

This is in contrast to my first jab where I felt poorly for a couple days following it.

 

 

Edited April 23, 2021 by friendlyone

[WilliamChew]

Just curious if anyone feels the need to refrain from alcohol after vaccination.

 

This post on Jan 1 has a link by the New Scientist that recommended not to take alcohol after vaccination as it acts as an immune suppressant.

 

Also from Healthline:

Experts in the United Kingdom recently warned that people should avoid drinking alcohol in the days before and after receiving the COVID-19 vaccine. “You need to have your immune system working tip-top to have a good response to the vaccine, so if you’re drinking the night before, or shortly afterwards, that’s not going to help,” Sheena Cruickshank, PhD, an immunologist at the University of Manchester, told UK Metro.

 

A Russian health official went even further last month and advised citizens being vaccinated with the country’s Sputnik V vaccine that they should abstain from alcohol for two months.

 

Experts in the United States, however, say that for people who do not use alcohol excessively, this is likely unnecessary.

 

Edited April 23, 2021 by WilliamChew

[AH173]

1 hour ago, WilliamChew said:

Just curious if anyone feels the need to refrain from alcohol after vaccination.

The Dr who gave me my 2nd Moderna told me not to consume alcohol until next day. 

[Sofia]

10 hours ago, Hope said:

I had my first C-19 jab this afternoon- Pfizer. They were giving them free at my workplace. 

 

I feel pretty good. I might be feeling a little like I just took a swig of rum... 🤔 It's a couple hours later and I just feel sorta tired. 

 

I also discovered that my job is probably ending next Friday, so that could be it, too... 😥  But, I have meeting tonight- gitta get bright!  👍🏼😔

So sorry ... I too lost my job 3 years ago. Keep your flight high and put your trust in Jehovah ❤️

[Dustparticle]

I just had my second piece of chocolate a few minutes ago. I feel fine too.

[Tortuga]

9 hours ago, WilliamChew said:

Just curious if anyone feels the need to refrain from alcohol

That would be a new experience....

[New World Explorer]

Australian health authorities say another three cases of rare blood clots – including in an 80-year-old Victorian man – are very likely linked to the AstraZeneca vaccine.

The medicines regulator on Friday night said the suspected cases of thrombosis with thrombocytopenia syndrome (TTS) were in a 35-year-old New South Wales woman, a 49-year-old Queensland man and the 80-year-old.https://www.theguardian.com/australia-news/2021/apr/23/australian-authorities-say-three-new-cases-of-blood-clots-very-likely-linked-to-astrazeneca-vaccine

[trottigy]

https://www.nytimes.com/2021/04/23/health/johnson-vaccine-resume.html

 

Quote

At an advisory panel meeting about the blood-clotting issue on Friday, the C.D.C. reported that it had identified a total of 15 cases, including three deaths.

 

But the risk is considered extremely small — nearly eight million Americans have received the Johnson & Johnson vaccine — and the panel decided that the vaccine’s benefits far outweighed its risks. The panel also concluded that failing to use it would lead to more deaths than the clotting disorder might cause.

15 out of 8,000,000 and 3 deaths. I understand that COVID itself causes blood clotting in rare instances too. Good to take aspirin before taking this shot, eh.

[New World Explorer]

2 minutes ago, trottigy said:

Good to take aspirin before taking this shot, eh.

I was thinking the same, but not sure if this will be sufficient? Need to look into it....

[New World Explorer]

4 minutes ago, trottigy said:

15 out of 8,000,000 and 3 deaths.

It seems that ratio is similar across the board, in Australia 4 cases in total (so far) 1 death. 

[Sofia]

1 hour ago, trottigy said:

https://www.nytimes.com/2021/04/23/health/johnson-vaccine-resume.html

 

15 out of 8,000,000 and 3 deaths. I understand that COVID itself causes blood clotting in rare instances too. Good to take aspirin before taking this shot, eh.

If they had caught the virus, they would surely ended up in Hospital with severe COVID disease... so in the end it´s best to take the shot, no? or risk the disease? 

The choice is up to each one.

No doubt that the more look-a-like the SARS the vaccine is, the more is likely to cause severe effects.

In the end it´s the immune reaction that causes the trouble not the virus it self.