Covid-19 Vaccine Research, Development, Ingredients and Reactions

[Tortuga]

6 minutes ago, Lieblingskind said:

This is also good for a review:

 

https://wol.jw.org/en/wol/d/r1/lp-e/1102018456

 

Agreed. We would like to keep this topic on track, so it would be good to post any additional comments in the right topic, such as this one. 

https://jwtalk.net/topic/43710-be-upbuilding-and-positive/

[WilliamChew]

About 1/4 of above 60's in Singapore have not had the vaccine yet. The government is introducing walk in vaccinations to encourage the remaining to get vaccinated.

 

Walk-in vaccination service for seniors above 60, no booking required

 

Response from the older set has been "excellent", with nearly three-quarters of Singapore's 760,000 senior citizens aged 60 and above having had at least one jab or booked a slot already.

 

But there are still 280,000 among the group who have yet to book their vaccination appointments.

 

 

[RNGuzman]

On 5/26/2021 at 12:58 PM, Lieblingskind said:

Has anyone taken Johnson and Johnson? Maybe a poll can be started…

My husband and I had the Johnson and Johnson vaccine in April and the only side effect we had was a sore arm for a couple of days.

[Sofia]

[Evidence published between 26/05/2021 and 01/06/2021]

Not only deaths

A rough first estimate suggests that as much as 30% of the COVID-19 health burden could be due to COVID-induced disability, not death. Using the right indicators of disability and disease will help evaluate cost-effective strategies in different countries.

New variant names

The WHO announced a simpler naming system for SARS-CoV-2 variants. Each variant of concern or of interest will receive a name from the Greek alphabet. B.1.1.7, the variant first identified in Britain, will be known as Alpha and B.1.351, (first seen in South Africa), will be Beta. P.1, (first seen in Brazil) will be Gamma and B.1.671.2, the so-called Indian variant, is Delta.

Unequal viral loads

A German team analysed PCR samples of more than 25,000 cases with different symptom severities. They found that the youngest had a lower viral load than older subjects, and individuals who required hospitalization had higher viral loads over the entire time course. 8% of subjects had very high viral loads in the throat, and one third of them were pre-symptomatic, asymptomatic or mildly symptomatic.

Autoantibodies

A study finds that over 90% of critically ill COVID-19 patients had IgM antibodies reactive against 260 self-antigens expressed by different organs. These autoantibodies may be involved in the pathogenesis of severe COVID-19.

Indirect protection

Two studies (not yet peer reviewed) show that vaccinated individuals provide indirect protection to their household members. A study in Finland with vaccinated healthcare workers shows that mRNA-based vaccines not only prevented infections among vaccinated individuals but also (although to a lesser degree) among unvaccinated household members (43% of indirect protection by 10 weeks after the first dose). Another study in Scotland shows that household members of vaccinated HCWs had a lower risk of contracting COVID-19 compared to those of unvaccinated HCWs.

The force of T cells

An analysis of humoral (antibody) and cellular immune responses in healthcare workers vaccinated with mRNA vaccines shows that, despite a decrease in neutralizing capacity of antibodies against the B1.351 variant, no differences in CD4+ T-cell activation were observed. These results indicate that the mutations in B.1.1.7 and B.1.351 Spike do not evade T-cell-mediated immunity induced by vaccination with the original S protein.

Vaccinating teenagers?

A clinical trial with Pfizer’s mRNA vaccine in 12-to-15-year-old recipients showed a good safety profile and high efficacy against COVID-19. The study included 2,260 adolescents. 16 cases occurred in placebo group and none in vaccinated group. The vaccine has been cleared by EMA for its use in children ages 12-15.

Moderna will also seek authorization to EMA after announcing similar results.

Yes, but…

However, many health experts have been question ing the ethics- and the logic- of vaccinating teenagers in rich countries when vulnerable people in low- and middle-income countries have not been vaccinated. In this sense, Science identifies 4 actions to fight vaccine inequality, and how long this may take: i) donating doses through COVAX (weeks to months), ii) expanding production (months), iii) sharing knowledge (months to years), and iv) building plants worldwide (years).

This is serious....

 

https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(21)00164-6

 

Highlights:

•

Over 90% of critically ill COVID-19 patients have auto-reactive IgM antibodies

•

Auto-reactive IgM bind diverse targets across multiple organ types

•

IgM and complement component C4d are abundant in COVID-19 non-survivor lung tissue

•

COVID-19-associated auto-IgM fixes complement to induce cell death in vitro

 

If anyone needs explanation ask please. Thank you

[cme]

It was on the news today that the Moderna and the Pfiezer vaccine are in line for being FDA approved.

[WilliamChew]

4 reasons the B1617 Covid-19 strain spreads so easily

 

He uses one of the three versions of the B1617 strain - the second B16172 version - to show what makes this virus different. B16172 has appeared to overtake B16171 in local cases as well as those reported globally. The third version, B16173, is rare.

 

Characteristic 1: The virus' mutations help it to bind more easily with the ACE2 receptor

 

Characteristic 2: Decreasing binding to antibodies

 

Characteristic 3: A more stable spike protein

 

Characteristic 4: Improving cleavage rates

 

 

[califlorican]

8 hours ago, cme said:

It was on the news today that the Moderna and the Pfiezer vaccine are in line for being FDA approved.

I’m very curious to see how many who are hesitant about the vaccine will get it once it is FDA approved!

[friendlyone]

Quote

 

Covid: Zero daily deaths announced in UK for first time

 

The UK has announced zero daily Covid deaths within 28 days of a positive test for the first time since March 2020.

The latest figures also reported another 3,165 new cases, compared with 3,383 on Monday and 2,493 one week ago.

It comes amid concern over a recent small rise in cases linked to the variant first identified in India.

 

Reports of daily deaths are often lower at weekends and at the start of the week.

 

This is because less counting takes place while statisticians are off - and adding in the bank holiday weekend will make this figure less certain still.

 

Any deaths that happen on Tuesday will be reported in days to come

 

 

 

https://www.bbc.co.uk/news/uk-57320320

 

This is welcome news, though as the report points out the death toll might increase with updated figure due out later.

[Sofia]

Like I always said... this confirms my research:  

 

Had COVID? You’ll probably make antibodies for a lifetime!

 

https://www.nature.com/articles/d41586-021-01442-9?fbclid=IwAR3FmFgDRFxPKkjMc8HNz3W_n5NBq-rGEq-gDFXG36_9ay8gwsGELrSzHnM

 

 

[vern]

I will not change my mind regardless of FDA approval.  If it spread world wide so fast they way they were worried about;  most should have natural immunity.

[Shawnster]

39 minutes ago, vern said:

most should have natural immunity.

But that's not how all viruses work. Not everything is like chicken pox. If one has had the flu in the past, one can get flu again. Same with malaria, etc... 

 

With covid19 being so new, they still do not know how long any natural immunity will last.  People who had contracted this virus should not allow themselves to be lulled into a false sense of security by assuming they are now and forevermore immune to covid19 

[AH173]

26 minutes ago, Shawnster said:

assuming they are now and forevermore immune to covid19 

And it's multitudinous variants or mutations. 

[Naturale]

Blood samples from recovered patients suggest a powerful, long-lasting immune response, researchers reported.

How long might immunity to the coronavirus last? Years, maybe even decades, according to a new study — the most hopeful answer yet to a question that has shadowed plans for widespread vaccination.

Eight months after infection, most people who have recovered still have enough immune cells to fend off the virus and prevent illness, the new data show. A slow rate of decline in the short term suggests, happily, that these cells may persist in the body for a very, very long time to come.

The research, published online, has not been peer-reviewed nor published in a scientific journal. But it is the most comprehensive and long-ranging study of immune memory to the coronavirus to date.

“That amount of memory would likely prevent the vast majority of people from getting hospitalized disease, severe disease, for many years,” said Shane Crotty, a virologist at the La Jolla Institute of Immunology who co-led the new study...

And the research squares with another recent finding: that survivors of SARS, caused by another coronavirus, still carry certain important immune cells 17 years after recovering.

The findings are consistent with encouraging evidence emerging from other labs. Researchers at the University of Washington, led by the immunologist Marion Pepper, had earlier shown that certain “memory” cells that were produced following infection with the coronavirus persist for at least three months in the body.

A study published last week also found that people who have recovered from Covid-19 have powerful and protective killer immune cells even when antibodies are not detectable.

These studies “are all by and large painting the same picture, which is that once you get past those first few critical weeks, the rest of the response looks pretty conventional,” said Deepta Bhattacharya, an immunologist at the University of Arizona.

Akiko Iwasaki, an immunologist at Yale University, said she was not surprised that the body mounts a long-lasting response because “that’s what is supposed to happen.” Still, she was heartened by the research: “This is exciting news.”

https://www.nytimes.com/2020/11/17/health/coronavirus-immunity.html

[Shawnster]

21 minutes ago, Naturale said:

How long might immunity to the coronavirus last? Years, maybe even decades, according to a new study —

That would be a good thing.  Hopefully more studies will help verify this conclusion  

 

[Sofia]

2 hours ago, Shawnster said:

That would be a good thing.  Hopefully more studies will help verify this conclusion  

 

Based on the first SARS back in 2003, the imunity lasts.

People who got it then still had imunity after 18 years.

 

Sars cov 2 is 87% similar to SARS.

The mutations so far had NOT changed the virus so much... this is not like flu virus. not at all.

[Sofia]

4 hours ago, AH173 said:

And it's multitudinous variants or mutations. 

Let me explain a bit about variants for all of you understand.

 

1. Flu virus

   imagine a Renault car. there are several models, like scenic, megane, captur, twingo.

   If you see a scenic or a twingo, you know it´s a Renault car, but the models are diferent.

 

So our imune system knows its a flu virus, but each year it changes it´s look, so its not easly recognizable, this year looks a megane, next year, a twingo etc... so you need jabs every year to be protected.

 

2. Coronavirus SARS

   Imagine a Ford car. there are several models... but let´s be specific: Escort model

               you can have many options: Guia, gasoline, 2 doors, 4 doors, leather seats, or ... whatever.

   they can be different - inside, but always same model: escort. They all look the same. Even in the dark, even in the shadow. 

 So SARS variants are like this: same model, but inside different. From the outside, you see it´s a Ford model Escort.

so this is why I believe vaccines still work. 

As long as the Ford is Escort: no problem. 

 

if in the future the Ford changes model into Focus for instance ... well, then "houston, we have a problem"... Vaccines then wont work. Imunity will change.

 

Hope this has helped.

Edited June 2, 2021 by Sofia

[Hope]

@Sofia - I love your explanations! Muito obrigado 🥰

[Sofia]

36 minutes ago, Hope said:

@Sofia - I love your explanations! Muito obrigado 🥰

you are so wellcome! ❤️

[Dustparticle]

30 minutes ago, Sofia said:

you are so wellcome! ❤️

You do a good job sis. Like others, you have love for people and you want to inform them what is happening.

[Sofia]

16 minutes ago, Dustparticle said:

You do a good job sis. Like others, you have love for people and you want to inform them what is happening.

Ooh thank you! Yes.

i love to speak the truth and above all I love Jehovah and thank you all for being here ❤️ 

Sending a big chocolate tablet for you brother Glen 😊 

Edited June 3, 2021 by Sofia

[lovjahupepl]

On 3/29/2021 at 11:29 AM, lovjahupepl said:

I debated whether to share this.  Please look up "rare blood disorder after covid vaccine"

I looked it up after one of the friends we know was taken to hospital and found to have a low blood count.  Transfusion was suggested.  Now diagnosis with a rare blood disorder shortly after getting s h o t.  Not sure how long they will live. 😟 They look fine, acting normal.

Just an update:  The friend has passed away.  😟

[Ludwika]

16 minutes ago, lovjahupepl said:

Just an update:  The friend has passed away.  😟

We're so sorry to hear that. 🌹

[hatcheckgirl]

3 hours ago, lovjahupepl said:

Just an update:  The friend has passed away.  😟

So very sorry to hear this my sister.  Can anything be more saddening than this wretched disease, and human endeavours to contain it? The reality is in this world is life can be snuffed out so easily. We can’t help but do our best, and pray for the new world. 🌷

[Sofia]

6 hours ago, lovjahupepl said:

Just an update:  The friend has passed away.  😟

Deeply sorry 🌸💐💐💐😢

[WilliamChew]

Its only been a few days since Singapore allowed vaccination for 12+ year olds. The response has been good.

 

At least 3 in 4 eligible students have registered for Covid-19 vaccine so far
 

About 83 per cent of students taking their GCE O-, N- and A-Level examinations this year have booked slots, and about 75 per cent of JC1 (junior college) students and those in polytechnics have done the same, he added.