Covid-19 Vaccine Research, Development, Ingredients and Reactions

[Lee49]

https://www.usatoday.com/story/news/health/2020/12/12/pfizer-covid-vaccine-ingredient-list-nothing-too-surprising-there/6520511002/

 

Pfizer's COVID-19 vaccine ingredients are pretty standard, experts say

 Experts say the ingredients in the COVID-19 vaccine developed by Pfizer and German partner BioNTech, which was authorized Friday by the U.S. Food and Drug Administration, looks pretty standard for a vaccine.

Active ingredient

30 mcg of a nucleosidemodified messenger RNA (modRNA) encoding the viral spike (S) glycoprotein of SARS-CoV-2.

Fats

lipids (0.43 mg (4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate), 0.05 mg 2[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide, 0.09 mg 1,2-distearoyl-sn-glycero-3- phosphocholine, and 0.2 mg cholesterol)

Salts

0.01 mg potassium chloride

0.01 mg monobasic potassium phosphate

0.36 mg sodium chloride

0.07 mg dibasic sodium phosphate dihydrate

Sugar

6 mg sucrose  

“Nothing too surprising there,” said Dr. Matthew Heinz, a hospitalist based in Tucson, Arizona. “It’s a normal way of packaging up medications for people.”  

The only active ingredient in the vaccine is the messenger RNA encoding the viral spike of SARS-CoV-2. That describes the modified mRNA that contains the code for cells to make the spike protein specific to the virus that will help create antibodies to attack it.

[Qapla]

Due to the extreme cold it is stored at - it does not have, nor does it need, preservatives ... no heavy metals in this vaccine.

 

 

[pnutts]

On 12/3/2020 at 12:15 PM, Qapla said:

kielbasa sausage

I get a quality brand but it is a treat.

 

Shot in the dark...err arm.

 

I will wait ( not that I have any choice ) for Moderna or another vaccine as I do have health issues including allergic reactions and am sensitive to medications.

 

So far Moderna says it is safe for diabetics, heart disease, etc. and older ones ( I'm all the mentioned ).

We shall see if and when I can get a shot in the dark....arm which won't probably be before April at the earliest.

That gives time for the guinea pigs, err 1st hundred thousandssss to react.

[WilliamChew]

Singapore will be providing free vaccinations for all Singapore citizens and permanent residents. Our prime minister said he will be one of the first to get vaccinated.

 

Q: Why is the vaccination programme voluntary and not mandatory? How does the Government hope to encourage greater public acceptance of vaccination apart from getting it free?

A: Very few vaccinations are made mandatory, because the Government wants to respect people's choices, Health Minister Gan Kim Yong said. But the task force hopes to encourage everyone to be vaccinated since the Health Sciences Authority (HSA) and the expert committee on Covid-19 vaccination have concluded the Pfizer-BioNTech vaccine is effective and safe. . .

Q: What happens if the take-up rate of vaccination is low? Is there a target take-up rate?

A: There is no specific target at the moment. The target is as high a take-up rate as possible, Mr Gan said. The Government will attempt to reach out to all eligible Singaporeans and local residents to encourage them to be vaccinated, and will enhance public education and outreach to encourage as many to sign up as possible . . .

 

https://www.straitstimes.com/singapore/nuts-and-bolts-of-spores-covid-19-vaccine

 

 

 

Edited December 16, 2020 by WilliamChew

[sunshine]

On 12/14/2020 at 9:34 PM, AH173 said:

I maybe wrong but does (most, some or few) grocery stores and supermarkets have the super cold (-80 to -100 F) Freezers?

They will still need to be properly equipted since usually vaccines can only be admininstered where resusciation equipment is present.  Still since this is an emergency they may change that rule for supermarkets.  

[Bob]

On ‎12‎/‎11‎/‎2020 at 5:28 PM, sunshine said:

 

I think it's a fair comment, so much depends on what we learn from the trials.  The spokesman for the British government Mat Hancock explained they dont yet know if the vaccine stops transmission. As the Pziter trial continues experts will be able to study the long term effects and learn more.

Well, vaccines don't really stop transmission as far as I understand. Its supposed to prevent illness. The Pfizer vaccine does this by injecting you with a fake Covid spike protein (no, this is not a weakened form of COVID) so that if/when you contract REAL COVID, you'll fight it off without really knowing it.

 

What they should be studying is if you get severely ill after getting both shots and building the sufficient immune response. That's what will save lives. Transmitting dead or non-infectious COVID, I believe, is inevitable.

 

That's why we want immunity.

Edited December 16, 2020 by Bob

[Bob]

On ‎12‎/‎11‎/‎2020 at 1:01 PM, Tortuga said:

The professors comment confuses me. She says there is no cause for alarm but she personally wont take the vaccine for a year because they want to see if it works. What is she waiting for?

I work for a healthcare company, and we had a video released this week discussing this very point. Its critical for professionals and healthcare workers to get the vaccine really as soon as they can, because the rest of the country is watching them. If healthcare workers and professionals are showing signs of hesitancy, then how can they expect the average person to trust it?

 

That was covered specifically. As soon as my shots come available, I'll take it though I'm young (under 40) and have no health conditions. I want to encourage my family to take it so I'll set an example.

[Sally]

Opinion Based on Scriptures

 

If they were using this "vaccine" for nefarious purposes, they would have a selection system. Health care workers would be exempt so I'd assume that they would get a normal saline injection as would other "essential people". Yes, they did this in Nazi Germany. Jehovah says of this time, "“a tribulation such as has not occurred from the beginning of the creation that God created until that time, and will not occur again.”—Mark 13:19; Daniel 12:1

Because of these scriptures, I had wondered how the holocaust could be topped by Satan....   

 

[zoebarry]

A healthcare worker in Alaska suffered a severe allergic reaction after receiving Pfizer’s coronavirus vaccine this week, The New York Timesreported. 
 

This individual in Alaska has no history of drug allergies, the newspaper reported, but it was not yet known if they suffered from other severe allergies.
 

Link to article

[Dustparticle]

5 hours ago, Bob said:

I work for a healthcare company, and we had a video released this week discussing this very point. Its critical for professionals and healthcare workers to get the vaccine really as soon as they can, because the rest of the country is watching them. If healthcare workers and professionals are showing signs of hesitancy, then how can they expect the average person to trust it?

 

That was covered specifically. As soon as my shots come available, I'll take it though I'm young (under 40) and have no health conditions. I want to encourage my family to take it so I'll set an example.

That is good to hear, yet many friends are not going to take it. So, I wonder how will they open up the halls again if they are not going to take it?

[Lee49]

"I wonder how will they open up the halls again if they are not going to take it?"

 

Maybe we'll have separate meetings, in house for those that have been vaccinated and zoom meetings for those that haven't, or sell all the KH's and continue with zoom meetings only, things can change fast as was noted in a recent talk " who would have thought that we would be using electronics to such a degree as we are now"? A big cost savings also!

[Bob]

57 minutes ago, Dustparticle said:

That is good to hear, yet many friends are not going to take it. So, I wonder how will they open up the halls again if they are not going to take it?

But many will take it. Its a personal choice, as we all know. Hall reopening will be determined based on case load in the community and transmission rates. If transmission rates are low enough and remain low for long enough, they'll reopen the halls. 

Edited December 17, 2020 by Bob

[SUNRAY]

4 hours ago, zoebarry said:

A healthcare worker in Alaska suffered a severe allergic reaction after receiving Pfizer’s coronavirus vaccine this week, The New York Timesreported. 
 

This individual in Alaska has no history of drug allergies, the newspaper reported, but it was not yet known if they suffered from other severe allergies.
 

Link to article

https://www.google.com/amp/s/mobile.reuters.com/article/amp/idUSKBN28J1DK

"However, the allergic reactions may have been caused by a component of Pfizer's vaccine called polyethylene glycol, or PEG, which helps stabilise the shot and is not in other types of vaccines."

[Dustparticle]

38 minutes ago, Bob said:

But many will take it. Its a personal choice, as we all know. Hall reopening will be determined based on case load in the community and transmission rates. If transmission rates are low enough and remain low for long enough, they'll reopen the halls. 

Good points, yet certain areas the cases were very low and still the halls were closed. Just have to wait and see.

[Bob]

Just now, Dustparticle said:

Good points, yet certain areas the cases were very low and still the halls were closed. Just have to wait and see.

Agree. We will have to wait and see. And the Slave did say they will be more cautious than the world so it could be a while as well. 

[Shawnster]

1 hour ago, Dustparticle said:

That is good to hear, yet many friends are not going to take it. So, I wonder how will they open up the halls again if they are not going to take it?

Plus, those "many" might not be that many after all, and some may change their mind as more and more people become vaccinated and return to a fuller life than we have now.

[rocket]

6 hours ago, zoebarry said:

A healthcare worker in Alaska suffered a severe allergic reaction after receiving Pfizer’s coronavirus vaccine this week, The New York Timesreported. 
 

This individual in Alaska has no history of drug allergies, the newspaper reported, but it was not yet known if they suffered from other severe allergies.
 

Link to article

Because of the allergic reaction "She was given Benadryl, Pepcid and epinephrine, and was kept overnight. "During the whole time, she was still enthusiastic that she got the vaccine and the benefits that it would give her in the future," 

https://www.cbsnews.com/news/covid-vaccine-allergic-reaction-alaska-health-care-worker/

[kejedo]

6 hours ago, zoebarry said:

A healthcare worker in Alaska suffered a severe allergic reaction after receiving Pfizer’s coronavirus vaccine this week, The New York Timesreported. 
 

This individual in Alaska has no history of drug allergies, the newspaper reported, but it was not yet known if they suffered from other severe allergies.
 

Link to article

I have severe allergies and anaphylaxis. I doubt my primary will refer me. I have no history of drug allergies, but environmental (oh, brother!) Below = Eye hives from being in an elevator with perfume. I subsequently fell (blocked eyesight.) Perfume allergy was previously determined in a medical facility when a perfume laden nurse came in to draw blood. Doc came in and asked her to leave. (Years before this episode.)

 

 

[Bob]

Just now, rocket said:

Because of the allergic reaction "She was given Benadryl, Pepcid and epinephrine, and was kept overnight. "During the whole time, she was still enthusiastic that she got the vaccine and the benefits that it would give her in the future," 

https://www.cbsnews.com/news/covid-vaccine-allergic-reaction-alaska-health-care-worker/

Yeah, I'm not overly concerned about side-affects, as they mean the vaccine is working. But I DO recall reading this week that people known to have severe allergic reactions should probably not take the vaccine. 

 

But again, its up to the person. 

[kejedo]

I usually carry a couple of epipens and have liquid benadryl in my cabinet. One of my Bible Students is an EMT. She said they have patients chew Benadryl. If I get to the eye hive stage, I drink some liquid benadryl. Sorry if this is OT.

Edited December 17, 2020 by kejedo

[Jothob]

Personally I can’t see the brothers giving the go-ahead to open KH’s for a long time yet. 
After all our meetings are for the general public as well so we couldn’t physically stop anyone coming in to a meeting. Now, what if that person doesn’t know they are carrying the virus and brings it into the KH! 
I can’t see it to be honest, I think the GB are being very cautious to keep crowds apart for now. 

[sunshine]

19 hours ago, Bob said:

Well, vaccines don't really stop transmission as far as I understand. Its supposed to prevent illness. The Pfizer vaccine does this by injecting you with a fake Covid spike protein (no, this is not a weakened form of COVID) so that if/when you contract REAL COVID, you'll fight it off without really knowing it.

 

What they should be studying is if you get severely ill after getting both shots and building the sufficient immune response. That's what will save lives. Transmitting dead or non-infectious COVID, I believe, is inevitable.

 

That's why we want immunity.

 

 

 

Yes exactly, so once the entire world is vaccinated we will be able to crunch the numbers and see if less people die after than die before.    Obviously it is so deadly, we cannot develop immunity naturally...I forget the actual survival rate, but it must be every low.  This way immunity  can be developped  in a controlled manner once -  they find out the effect of the vaccine long term.  Its a new technology so it must be rolled out globally to full study what it will do to people and children long term. 

 

Edited December 17, 2020 by sunshine

[sunshine]

6 hours ago, Jothob said:

Personally I can’t see the brothers giving the go-ahead to open KH’s for a long time yet. 
After all our meetings are for the general public as well so we couldn’t physically stop anyone coming in to a meeting. Now, what if that person doesn’t know they are carrying the virus and brings it into the KH! 
I can’t see it to be honest, I think the GB are being very cautious to keep crowds apart for now. 

Bill Gates Said in a recent CNN interview he envisioned a possible retire to normal (no masks, no social distancing) by the sommer of 2022 if there is a high uptake of the vaccine all over the world.  Our brother are extra cautions so probably only have another 2 or 3 years before brings get back to normal.

 

 

[Naturale]

1 hour ago, sunshine said:

Obviously it is so deadly, we cannot develop immunity naturally...I forget the actual survival rate, but it must be every low. 

 

Immunity to the Coronavirus May Last Years, New Data Hint

Blood samples from recovered patients suggest a powerful, long-lasting immune response, researchers reported.

How long might immunity to the coronavirus last? Years, maybe even decades, according to a new study — the most hopeful answer yet to a question that has shadowed plans for widespread vaccination.

Eight months after infection, most people who have recovered still have enough immune cells to fend off the virus and prevent illness, the new data show. A slow rate of decline in the short term suggests, happily, that these cells may persist in the body for a very, very long time to come.

The research, published online, has not been peer-reviewed nor published in a scientific journal. But it is the most comprehensive and long-ranging study of immune memory to the coronavirus to date.

“That amount of memory would likely prevent the vast majority of people from getting hospitalized disease, severe disease, for many years,” said Shane Crotty, a virologist at the La Jolla Institute of Immunology who co-led the new study...

And the research squares with another recent finding: that survivors of SARS, caused by another coronavirus, still carry certain important immune cells 17 years after recovering.

The findings are consistent with encouraging evidence emerging from other labs. Researchers at the University of Washington, led by the immunologist Marion Pepper, had earlier shown that certain “memory” cells that were produced following infection with the coronavirus persist for at least three months in the body.

A study published last week also found that people who have recovered from Covid-19 have powerful and protective killer immune cells even when antibodies are not detectable.

These studies “are all by and large painting the same picture, which is that once you get past those first few critical weeks, the rest of the response looks pretty conventional,” said Deepta Bhattacharya, an immunologist at the University of Arizona.

Akiko Iwasaki, an immunologist at Yale University, said she was not surprised that the body mounts a long-lasting response because “that’s what is supposed to happen.” Still, she was heartened by the research: “This is exciting news.”

https://www.nytimes.com/2020/11/17/health/coronavirus-immunity.html

[rocket]

https://www.nytimes.com/2020/11/17/health/coronavirus-immunity.html

 

That article is full of maybe's.  The fact is that there are those who have gotten the virus a second time after only a few months. Some have died the second time around and some have found the symptoms were worse the second time and there were those who still have antibodies man months after.

 

https://www.webmd.com/lung/news/20200824/study-confirms-its-possible-to-catch-covid-twice

https://www.cnn.com/2020/10/16/health/coronavirus-reinfections-what-we-know-wellness/index.html

https://www.usatoday.com/story/news/health/2020/11/13/covid-19-reinfection-vaccines-herd-immunity-health/6136943002/

https://www.today.com/health/covid-19-reinfection-can-you-get-coronavirus-twice-what-does-t190764

Edited December 17, 2020 by rocket